AUGUST 2003 Editorial

The cream of the world’s genetics community converged on Melbourne in their thousands last month for the “Olympics of Genetics”, an international conference held every 5 years.

The conference coincided with the 50th anniversary since James Watson and Francis Crick determined the structure of DNA. It was also the first time that the conference had been held since researchers had sequenced the three billion nucleotides that make up the human genome.

The conference should have been a celebration, but it was marked by angst over the directions the field is taking, and who is leading it there.

Nobel Laureates like John Sulston teamed with Francis Collins, who led the international effort to sequence the human genome and keep it in public hands, in their condemnation of the privatisation of the genome through the patent system. Their chief whipping boy was Malcolm Simons, the Australian maverick who patented 95% of the genome in the mid-1990s when non-coding DNA was considered junk.

But one man’s trash is another man’s treasure, and geneticists are now finding there is much more to non-coding DNA and are alarmed that the company Simons cofounded, Genetics Technologies, is now enforcing its patents.

But while the geneticists argued over the principle of public ownership of DNA, there was little input from the legal community. Legal opinion was restricted to a forum on privacy issues raised by genetics, but otherwise debate over DNA patenting was left to the scientists.

While this month Australasian Science features a special section on the research presented at the 19th International Congress of Genetics, we have gone outside the conference for legal comment on the issue of access to DNA in the genome age.

Matthew Rimmer, an intellectual property lecturer specialising in agriculture, reveals that the issue is not confined to the human genome. Rather, private companies are rapidly moving in on other important genomes, such as rice, with important ramifications for food security.

The companies that have sequenced these genomes are hiding behind a combination of contract law, copyright law and patent law to control access to sequence databases. Already most geneticists say that their requests for data are being refused.

The sequencing of the genome promised to open up new horizons for researchers throughout the world. Unless they can band together to form a fighting fund to challenge these patents in court it seems many of these horizons will be left unexplored until the patents expire in coming decades.

Even then scientists will need thorough legal advice to ensure their research doesn’t infringe someone else’s intellectual property. Genetics Technologies, for instance, has already identified thousands of potential infringements of its patents.

Guy Nolch
Editor

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